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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
23.64
Human Site:
S628
Identified Species:
34.67
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
S628
P
F
Q
S
H
D
R
S
L
T
C
T
S
A
V
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
S720
P
F
Q
S
H
D
R
S
L
T
C
T
S
A
V
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
S880
P
F
Q
S
H
D
R
S
L
T
C
T
S
A
V
Dog
Lupus familis
XP_547953
806
90703
S635
P
F
Q
S
H
D
K
S
L
T
C
T
S
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S604
V
I
L
Y
M
M
L
S
G
Q
V
P
F
Q
G
Rat
Rattus norvegicus
Q63531
735
82865
F558
E
C
L
R
I
C
D
F
G
F
A
K
Q
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S545
P
F
Q
S
H
D
K
S
L
T
C
T
N
A
V
Chicken
Gallus gallus
Q5F3L1
789
89022
S618
P
F
Q
S
Q
D
K
S
L
T
C
T
S
A
L
Frog
Xenopus laevis
P10665
733
82620
R563
F
G
F
A
K
Q
L
R
A
D
N
G
L
L
M
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
T575
G
D
N
G
L
L
L
T
P
C
Y
T
A
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D827
R
Q
N
E
D
D
V
D
H
S
A
A
A
H
H
Honey Bee
Apis mellifera
XP_395099
910
102507
D647
P
F
G
S
G
S
P
D
L
A
T
R
I
R
A
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
R594
G
Q
V
P
F
H
A
R
S
R
Q
E
S
A
T
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
I588
V
P
F
Q
D
P
S
I
S
K
S
N
S
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
E307
T
T
E
Y
M
A
P
E
I
V
R
G
K
G
H
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
I513
P
E
Y
L
A
P
E
I
L
L
G
Q
G
Y
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
93.3
N.A.
6.6
0
N.A.
86.6
80
0
6.6
N.A.
6.6
26.6
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
6.6
0
N.A.
100
93.3
13.3
20
N.A.
20
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
7
7
0
7
7
13
7
13
50
7
% A
% Cys:
0
7
0
0
0
7
0
0
0
7
38
0
0
0
0
% C
% Asp:
0
7
0
0
13
44
7
13
0
7
0
0
0
0
0
% D
% Glu:
7
7
7
7
0
0
7
7
0
0
0
7
0
0
0
% E
% Phe:
7
44
13
0
7
0
0
7
0
7
0
0
7
0
7
% F
% Gly:
13
7
7
7
7
0
0
0
13
0
7
13
7
7
7
% G
% His:
0
0
0
0
32
7
0
0
7
0
0
0
0
7
13
% H
% Ile:
0
7
0
0
7
0
0
13
7
0
0
0
7
0
0
% I
% Lys:
0
0
0
0
7
0
19
0
0
7
0
7
7
0
0
% K
% Leu:
0
0
13
7
7
7
19
0
50
7
0
0
7
13
7
% L
% Met:
0
0
0
0
13
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
7
7
7
7
0
% N
% Pro:
50
7
0
7
0
13
13
0
7
0
0
7
0
0
0
% P
% Gln:
0
13
38
7
7
7
0
0
0
7
7
7
7
7
0
% Q
% Arg:
7
0
0
7
0
0
19
13
0
7
7
7
0
7
7
% R
% Ser:
0
0
0
44
0
7
7
44
13
7
7
0
44
0
7
% S
% Thr:
7
7
0
0
0
0
0
7
0
38
7
44
0
0
13
% T
% Val:
13
0
7
0
0
0
7
0
0
7
7
0
0
0
32
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
0
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _